Director of Pediatric Genetics, Department of Pediatrics, and Cytogeneticist, The Harvey Institute for Human Genetics, Greater Baltimore Medical Center, MD
Consulting Geneticist, Dept. of Pediatrics, Sinai Hospital, Baltimore, MD
Consulting Geneticist, Sheppard Pratt Hospital, Baltimore, MD
Consulting Geneticist, Kennedy Krieger Institute, Baltimore, MD
Instructor in Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD
Clinical Assistant Professor, University of Maryland School of Medicine, Baltimore, MD

The Harvey Institute for Human Genetics
Greater Baltimore Medical Center
6701 North Charles St., Suite 2315
Baltimore, MD 21204
http://www.gbmc.org/body.cfm?id=38&action=detail&ref=239

Biosketch:

Dr. Kline received her medical degree from Jefferson Medical College, Philadelphia, PA, her postdoctoral training in medical genetics at Jefferson Medical College, Philadelphia, PA, her clinical cytogenetics training at the Kennedy Krieger Institute of the Johns Hopkins University School of Medicine, Baltimore, MD. She is board-certified in clinical genetics, clinical cytogenetics, and clinical molecular genetics. She is also a Fellow of the American Academy of Pediatrics and a Founding Fellow of the American College of Medical Genetics.

Dr. Kline's area of expertise includes evaluation of multiple birth defects and/or developmental issues, as well as correlation and interpretation of cytogenetic changes in a clinical setting. She is the medical director of the Cornelia de Lange Syndrome Foundation, and a member of the professional advisory board of the 5p- Society. She is also co-medical director of The Greater Baltimore Cleft Lip and Palate Team.

Declared conflict of interest on file (09/17/2022)

Selected Bibliography:

Roshan Lal T, Kliewer MA, Lopes T, Rebsamen SL, O’Connor J, Grados MA, Kimball A, Clemens J, Kline AD. .
Cornelia de Lange syndrome: correlation of brain MRI findings with behavioral assessment .
Am J Med Genet C. 2016.

Kline AD, Calof AL, Lander AD, Gerton JL, Krantz ID, Dorsett D, Deardorff MA, Blagowidow N, Yokomori K, Shirahige K, Santos R, Woodman J, Megee PC, O'Connor JT, Egense A, Noon S, Belote M, Goodban MT, Hansen BD, Timmons JG, Musio A, Ishman SL, Bryan Y, Wu Y, Bettini LR, Mehta D, Zakari M, Mills JA, Srivastava S, Haaland RE.
Clinical, developmental and molecular update on Cornelia de Lange syndrome and the cohesin complex: abstracts from the 2014 Scientific and Educational Symposium.
Am J Med Genet A. 2015;167(6):1179-92. PubMed abstract

Kline AD, Calof AL, Schaaf CA, Krantz ID, Jyonouchi S, Yokomori K, Gauze M, Carrico CS, Woodman J, Gerton JL, Vega H, Levin AV, Shirahige K, Champion M, Goodban MT, O'Connor JT, Pipan M, Horsfield J, Deardorff MA, Ishman SL, Dorsett D.
Cornelia de Lange syndrome: further delineation of phenotype, cohesin biology and educational focus, 5th Biennial Scientific and Educational Symposium abstracts.
Am J Med Genet A. 2014;164A(6):1384-93. PubMed abstract

Kline AD, Grados M, Sponseller P, Levy HP, Blagowidow N, Schoedel C, Rampolla J, Clemens DK, Krantz I, Kimball A, Pichard C, Tuchman D.
Natural history of aging in Cornelia de Lange syndrome.
Am J Med Genet C Semin Med Genet. 2007;145C(3):248-60. PubMed abstract

Kline AD, Krantz ID, Sommer A, Kliewer M, Jackson LG, FitzPatrick DR, Levin AV, Selicorni A.
Cornelia de Lange syndrome: clinical review, diagnostic and scoring systems, and anticipatory guidance.
Am J Med Genet A. 2007;143A(12):1287-96. PubMed abstract